Searchable abstracts of presentations at key conferences in endocrinology

ea0081p346 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Combination study of apoptosis gene polymorphisms in mitochondrial diabetes: Potential role in the pathogenesis of mitochondrial diabetes

Kacem Akid Faten Haj , Mohamed Ahmed Mohamed Abdellahi , Nesrine Dhieb , S Youssef , E Mkaouar-Rebai , F Fakhfakh , Mnif Mouna , Abid Mohamed

Introduction: Mitochondrial diabetes (DM) is a monogenic form of maternal transmission diabetes that is caused by mutations in the mitochondrial genome. These mutations affecting mitochondrial function may be the cause of initiation of the phenomenon of apoptosis itself having an aggravating role of the phenotype in patients with mitochondrial diabetes.Materials and Methods: This study involved 43 patients with mitochondrial diabetes (20 non-syndromic an...